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Skin wound healing

The inefficient healing of chronic wounds is a result of poor blood perfusion at the wound and surrounding tissues.

During CO2 therapy the LD flux in the studied extremity increased from 5.8 PU ± 3.9 PU to 30.3 PU ± 16.7 PU

CONCLUSIONS: Our results confirm a local vasodilatory effect of applied CO2 therapy.

Diabetic foot. It is the most common foot injury in diabetic patients and can lead to lower-extremity amputation.

Carboxytherapy refers to the subcutaneous injection of CO2 to improve the microcirculation and promote wound-healing by stimulating the microcirculation

The results showed that this treatment that included carboxytherapy promoted wound-healing and prevented amputation.

In their study, 42 patients were divided into three groups: A, B, and C.

In Group A, only liposuction was performed.

In group B 3 weeks after liposuction CO2 therapy was administered in two weekly subcutaneous applications of CO2 for 10 consecutive weeks.

In group C, CO2 therapy alone was administered with the same contingencies used for group B (two weekly subcutaneous applications of CO2 for 10 consecutive weeks)

This study has shown that with CO2 therapy to obtain improvement in skin irregularity and cutaneous elasticity is possible.

Our study has shown the positive response to reduced fat accumulation.
This was confirmed by analysis of the results obtained by measurement of thigh circumference in group B than in group A.

Particularly interesting were the effects on skin elasticity

“It seems essential to use procedures stimulating the production of collagen, such as radiofrequency, intense light source, LED light (light-emitting diode), IR (infrared light), laser treatments, and chemical peels in activities aiming to improving skin elasticity.

Nevertheless, none of these treatments has long-lasting effects related to the improvement of skin microcirculation which seems to be a factor necessary for proper functioning of various cells, including fibroblasts.

It has been demonstrated that carboxytherapy improves cutaneous circulation, which is mirrored by overall improvement of skin function. Brandi et al. performed a study, in which local application of carbon dioxide was associated with a mean increase in skin elasticity by 55%.

In other study by Brandi et al., subcutaneous and intradermal administration of carbon dioxide resulted in the increase in the production of new collagen and the degradation of old one.

The arrangement of new collagen was characteristic for the skin of young organisms. Studies have also demonstrated the appearance of new capillary vessels (Brandi et al., 2001, 2004, 2012).”

“Carboxytherapy seems to be the only method that affects all signs of skin aging, including the loss of skin elasticity, wrinkles, shadows, swelling, and fat hernia under the eyes.”